Caprolactam → Laurocapram

HRID 1447391

반응식

HRID 1447391 반응식
[H-].[Na+].[NH:3]1[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][C:4]1=[O:10].Br[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>>[CH2:23]([N:3]1[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][C:4]1=[O:10])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH3:12]

참가 물질

4

반응물 3

HCID 7768CaprolactamHCID 89191-BromododecaneHCID 24758Sodium hydride2회

생성물 1

HCID 42981Laurocapram수율 80.4%

실험 절차

Following example 10, 15.3 g of 50% sodium hydride-mineral oil dispersion (7.65 g NaH, 0.319 M), 30 g (0.266 M) of azacycloheptan-2-one and 66.1 g (0.265 M) of 1-bromododecane on 20 hr. reflux gave 60 g (80%) of colorless product; b.p. 175°-180°/0.3 mm.

후처리

  1. customon 20 hr
  2. temperaturereflux

출처 및 근거

ORD 기록
ord-fb5d2a8c8f63409bbd111d8d6a59a144
출처 데이터셋
uspto-grants-1982_02
특허 번호
US04316893

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