2-Amino-2-methyl-1-propanol → N-(2-hydroxy-1,1-dimethylethyl)-2-(isopropyl)-5-methylcyclohexanecarboxamide

HRID 1447842노트

반응식

HRID 1447842 반응식
[CH:1]1([CH3:13])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([C:10](Cl)=[O:11])[CH2:2]1.[NH2:14][C:15]([CH3:19])([CH3:18])[CH2:16][OH:17]>>[CH3:18][C:15]([NH:14][C:10]([CH:3]1[CH:4]([CH:7]([CH3:9])[CH3:8])[CH2:5][CH2:6][CH:1]([CH3:13])[CH2:2]1)=[O:11])([CH3:19])[CH2:16][OH:17]

참가 물질

3

반응물 2

HCID 118072-Amino-2-methyl-1-propanolHCID 13734319Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)-

생성물 1

HCID 3016105N-(2-hydroxy-1,1-dimethylethyl)-2-(isopropyl)-5-methylcyclohexanecarboxamide

실험 절차

p-Menth-3-oyl chloride (3.0 g.) was reacted with 2-amino-2-methyl-propan-1-ol (3.0 g.) according to the procedure of Example 3. Product N-(1,1-dimethyl-2-hydroxyethyl)-p-menthane-3-carboxamide was obtained as a crystalline solid which was recrystallised from aqueous methanol. M.p. 123°.

출처 및 근거

ORD 기록
ord-aff735b151a04e189e4dbb0a9c5020dc
출처 데이터셋
uspto-grants-1979_12
특허 번호
US04178459

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