HCID 12401704, 화합물 → 4-oxo-4H-chromene-2-carbaldehyde

HRID 1447987노트

반응식

HRID 1447987 반응식
C[O:2][CH:3](OC)[C:4]1[O:5][C:6]2[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=2[C:8](=[O:10])[CH:9]=1>Cl>[O:5]1[C:6]2[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=2[C:8](=[O:10])[CH:9]=[C:4]1[CH:3]=[O:2]

참가 물질

3

반응물 1

HCID 12401704HCID 12401704, 화합물

생성물 1

HCID 104196624-oxo-4H-chromene-2-carbaldehyde수율 81.6%

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

A stirred solution of 2-(dimethoxymethyl)-4H-1-benzopyran-4-one (1.1 g, 0.005 m) in 5 N hydrochloric acid (20 ml) was heated at 100° for 3 hours. The reaction mixture was cooled and extracted with CHCl3. The extracts were dried over MgSO4 and evaporated under reduced pressure to give a crystalline product. Recrystallization from ethyl acetate gave off-white crystals (710 mg, 81%), m.p. 159°-161°.

후처리

  1. temperatureThe reaction mixture was cooled
  2. extractionextracted with CHCl3
  3. dry with materialThe extracts were dried over MgSO4
  4. customevaporated under reduced pressure
  5. customto give a crystalline product
  6. customRecrystallization from ethyl acetate

출처 및 근거

ORD 기록
ord-a1fd200c02da465981ea0f2a628e5cbc
출처 데이터셋
uspto-grants-1979_12
특허 번호
US04179447

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