Tiflamizole → HCID 86736848, 화합물

HRID 1449398노트

반응식

HRID 1449398 반응식
C[O-].[Na+].[Na:4].[F:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]([S:24]([C:27]([F:32])([F:31])[CH:28]([F:30])[F:29])(=[O:26])=[O:25])[NH:15][C:16]=2[C:17]2[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=2)=[CH:8][CH:7]=1>CCOCC>[Na:4].[F:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]([S:24]([C:27]([F:32])([F:31])[CH:28]([F:29])[F:30])(=[O:25])=[O:26])[NH:15][C:16]=2[C:17]2[CH:18]=[CH:19][C:20]([F:23])=[CH:21][CH:22]=2)=[CH:8][CH:7]=1

참가 물질

5

반응물 3

HCID 44188TiflamizoleHCID 5360545SodiumHCID 10942334Sodium Methoxide

생성물 1

HCID 86736848HCID 86736848, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A mixture of 4,5l -bis(4-fluorophenyl)-2-(1,1,2,2-tetrafluoroethylsulfonyl)imidazole (5.0 g., 0.0119 mole), sodium methoxide (0.6 g., 0.0111 mole) and ether (300 ml.) is stirred overnight at room temperature. The solid is collected and washed with ether to give 2.1 g. of the sodium salt of 4,5-bis(4-fluorophenyl)-2-(1,1,2,2-tetrafluoroethylsulfonyl)imidazole, m.p. 290°-292°.

후처리

  1. customThe solid is collected
  2. washwashed with ether
  3. customto give 2.1 g

출처 및 근거

ORD 기록
ord-bf450b271feb4328b14caf405da01dd2
출처 데이터셋
uspto-grants-1980_02
특허 번호
US04190666

반응 노트

불러오는 중…