Sodium Hydroxide → HCID 86750370, 화합물

HRID 1451095노트

반응식

HRID 1451095 반응식
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][C:8]([C:9]([O:11]C)=[O:10])=[CH:7][C:6]=1[CH:15]=[N:16][OH:17])(=[O:3])[CH3:2].[OH-].[Na+]>>[OH2:3].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][C:8]([C:9]([OH:11])=[O:10])=[CH:7][C:6]=1[CH:15]=[N:16][OH:17])(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 85177110HCID 85177110, 화합물

생성물 1

HCID 86750370HCID 86750370, 화합물수율 131.8%

실험 절차

A mixture of methyl 4-acetylamino-3-[(hydroxylimino)methyl]benzoate (142 mg, 0.6 mmol) and 1N sodium hydroxide (1.0 mL, 1.0 mmol) was stirred at room temperature for 4 h. The mixture was filtered through a pad of cotton and neutralized with dil. hydrochloric acid. The precipitate obtained was collected by filtration, washed with water, and dried under vacuum over acetone for 24 h to give 95 mg (71%) of the title compound as a white powder, mp 215°-218° C. (dec).

후처리

  1. filtrationThe mixture was filtered through a pad of cotton
  2. customThe precipitate obtained
  3. filtrationwas collected by filtration
  4. washwashed with water
  5. dry with materialdried under vacuum over acetone for 24 h

출처 및 근거

ORD 기록
ord-a0a84418c10d4d2aa3801e1b0499d2a2
출처 데이터셋
uspto-grants-1997_02
특허 번호
US05602277

반응 노트

불러오는 중…