Sodium Hydroxide → HCID 14076219, 화합물

HRID 1451402노트

반응식

[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([O:3]CC)=[O:2].[OH-].[Na+]>>[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([OH:3])=[O:2]

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 14076218HCID 14076218, 화합물

생성물 1

HCID 14076219HCID 14076219, 화합물

실험 절차

Prepared analogously to Example 2 by reaction of N-[2-(4-carboethoxyphenyl)ethyl]-2-hydroxy-2-(2-acetylamino-4-methyl-thiazol-5-yl)ethanamine with 1N sodium hydroxide solution. After neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness, and the residue is recrystallised from 10 ml of water.

후처리

customAfter neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness
customthe residue is recrystallised from 10 ml of water

출처 및 근거

ORD 기록: ord-21ab236f2fcd49ddb3f1fdee9981f9fc
출처 데이터셋: uspto-grants-1997_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05604225

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