Vinyl chloroformate → 2-vinyloxycarbonylamino-5-[pyridazin-3(2H)-on-6-yl]indane

HRID 1451780노트

반응식

HRID 1451780 반응식
[NH2:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:11]3[CH:12]=[CH:13][C:14](=[O:17])[NH:15][N:16]=3)[CH:8]=2)[CH2:3]1.Br.Cl[C:20]([O:22][CH:23]=[CH2:24])=[O:21]>>[CH:23]([O:22][C:20]([NH:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:11]3[CH:12]=[CH:13][C:14](=[O:17])[NH:15][N:16]=3)[CH:8]=2)[CH2:3]1)=[O:21])=[CH2:24]

참가 물질

3

반응물 2

HCID 78808Vinyl chloroformateHCID 189297722-amino-5-[pyridazin-3(2H)-on-6-yl]indane hydrobromide

생성물 1

HCID 199728402-vinyloxycarbonylamino-5-[pyridazin-3(2H)-on-6-yl]indane

실험 절차

2-Amino-5-[pyridazin-3(2H)-on-6-yl]indane·hydrobromide and vinyl chloroformate were treated in the same manner as in Example 49 to obtain 2-vinyloxycarbonylamino-5-[pyridazin-3(2H)-on-6-yl]indane.

출처 및 근거

ORD 기록
ord-8845cc75db104cf2ba35304fff899850
출처 데이터셋
uspto-grants-1997_02
특허 번호
US05605901

반응 노트

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