Hydrogen Bromide → 2-Bromo-4-ethyl-6-nitroaniline

HRID 1452049

반응식

HRID 1452049 반응식
[CH2:1]([C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[C:5]([N+:10]([O-:12])=[O:11])[CH:4]=1)[CH3:2].[BrH:13].BrBr>O>[CH2:1]([C:3]1[CH:9]=[C:8]([Br:13])[C:6]([NH2:7])=[C:5]([N+:10]([O-:12])=[O:11])[CH:4]=1)[CH3:2]

참가 물질

5

반응물 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 2516744-Ethyl-2-nitroaniline

생성물 1

HCID 199734682-Bromo-4-ethyl-6-nitroaniline

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
7 °C

실험 절차

5-Ethyl-7-bromo-4-[benzenesulfonimide]-1,4-dihydroquinoline-2-carboxylic acid, ethyl ester ##STR24## Mix 4-ethyl-2-nitroaniline (16.6g, 0.1mol) in water (400mL) and add 48% hydrobromic acid (1kg). Add bromine (16g, 0.1mol) with stirring and stir for 1 hour. Dilute to 2L and cool to 7° C. Filter, wash with water and dry to give 4-ethyl-2-nitro-6-bromoaniline.

후처리

  1. filtrationFilter
  2. washwash with water
  3. customdry

출처 및 근거

ORD 기록
ord-830a3608bdd9453eba333810836ebcfd
출처 데이터셋
uspto-grants-1997_02
특허 번호
US05606063

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