Dimethyl Sulfate → (R)-3-methoxydihydro-2H-pyran-4(3H)-one

HRID 1452533노트

반응식

HRID 1452533 반응식
C[O:2][C:3]1(OC)[CH2:8][CH2:7][O:6][CH2:5][CH:4]1[OH:9].[CH3:12]C([O-])(C)C.[Na+].COS(OC)(=O)=O>C1COCC1>[CH3:12][O:9][C@H:4]1[C:3](=[O:2])[CH2:8][CH2:7][O:6][CH2:5]1

참가 물질

5

반응물 3

HCID 6497Dimethyl SulfateHCID 121909884,4-Dimethoxytetrahydro-2H-pyran-3-olHCID 23676156Sodium t-butoxide

생성물 1

HCID 11320949(R)-3-methoxydihydro-2H-pyran-4(3H)-one

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

reacting said 4,4-dimethoxytetrahydro-2H-pyran-3-ol in the presence of THF, NaOt-Bu, Me2SO4, and an acid to form (3R)-3-methoxytetrahydro-4H-pyran-4-one.

출처 및 근거

ORD 기록
ord-31bb9e50772947e481a40a3b35fdad22
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07473696B2

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