4-Methoxy-3-methylbenzoic Acid → 4-Methoxy-3-methyl-N-(1-pyridin-2-yl-butyl)-benzamide

HRID 1453497

반응식

HRID 1453497 반응식
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][C:4]=1[CH3:12].[N:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH:19]([NH2:23])[CH2:20][CH2:21][CH3:22]>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH:23][CH:19]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][N:13]=2)[CH2:20][CH2:21][CH3:22])=[O:9])=[CH:5][C:4]=1[CH3:12]

참가 물질

3

반응물 2

HCID 27595834-Methoxy-3-methylbenzoic AcidHCID 227675931-(Pyridin-2-yl)butan-1-amine

생성물 1

HCID 575277554-Methoxy-3-methyl-N-(1-pyridin-2-yl-butyl)-benzamide

실험 절차

Prepared in a similar manner to example 4 using 4-methoxy-3-methyl-benzoic acid and 1-pyridin-2-yl-butylamine. 1H NMR (500 MHz, CDCl3): δ 0.91-0.92 (t, 3H), 1.25-1.3 (m, 2H, 1.85-1.9 (m, 2H), 3.86 (s, 3H), 5.25-5.3 (m, 1H), 6.80-6.82 (d, 1H), 7.2-7.3 (m, 2H), 7.42-7.44 (d, 1H), 7.6-7.7 (m, 3H), 8.6 (d, 1H). MS (M+H, 299.1).

출처 및 근거

ORD 기록
ord-a00939b1c64e406db73a7c6cdb5a6d36
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07476399B2

연결된 노트

불러오는 중…