Hydrochloric Acid → HCID 66764225, 화합물
반응식
[Cl:1][C:2]1[N:7]=[N:6][C:5]([C:8]23[CH2:15][N:12]([CH2:13][CH2:14]2)[CH2:11][CH2:10][CH2:9]3)=[CH:4][CH:3]=1.CS[C:18]1[S:22][C:21](B(O)O)=[CH:20][CH:19]=1.Cl.[CH3:27]C(O)C>>[ClH:1].[CH3:27][C:18]1[S:22][C:21]([C:2]2[N:7]=[N:6][C:5]([C:8]34[CH2:15][N:12]([CH2:13][CH2:14]3)[CH2:11][CH2:10][CH2:9]4)=[CH:4][CH:3]=2)=[CH:20][CH:19]=1참가 물질
5
실험 절차
This compound is obtained according to the method described in stage 1.6 of Example 1, using 5-(6-chloropyridazin-3-yl)-1-azabicyclo[3.2.1]octane, prepared according to stage 1.5 of Example 1, and 5-methylsulfanyl-2-thienylboronic acid. The hydrochloride thereof is prepared by treatment of the base with a solution of hydrochloric acid in propan-2-ol, and the crystals obtained are collected by filtration and dried under vacuum.