4-(2-Methyl-4-nitrophenyl)-1,4-oxazepan-5-one → 3-Methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-aniline

HRID 1453659노트

반응식

HRID 1453659 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([N+:16]([O-])=O)[CH:5]=[CH:6][C:7]=1[N:8]1[C:14](=[O:15])[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1>[Ni].CO>[CH3:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[N:8]1[C:14](=[O:15])[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1)[NH2:16]

참가 물질

4

반응물 1

HCID 595867304-(2-Methyl-4-nitrophenyl)-1,4-oxazepan-5-one

생성물 1

HCID 595867743-Methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-aniline

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

Prepared analogously to Example 1c from 3-methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-1-nitro-benzene with Raney nickel under a hydrogen atmosphere in methanol.

출처 및 근거

ORD 기록
ord-fb5b4ff9ab614ce2b0f5f4d23cb8663f
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07476663B2

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