Triphenylphosphine → Triphenyl(3,3,3-trifluoropropyl)phosphanium iodide

HRID 1454080

반응식

HRID 1454080 반응식
[F:1][C:2]([F:7])([F:6])[CH2:3][CH2:4][I:5].[C:8]1([P:14]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C1(C)C=CC=CC=1>[I-:5].[F:1][C:2]([F:7])([F:6])[CH2:3][CH2:4][P+:14]([C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

참가 물질

4

반응물 2

HCID 11776TriphenylphosphineHCID 1561651,1,1-Trifluoro-3-iodopropane

생성물 1

HCID 19694095Triphenyl(3,3,3-trifluoropropyl)phosphanium iodide수율 92.5%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

A solution of 1,1,1-trifluoro-3-iodopropane (263.1 g, 1.17 moles) and triphenylphosphine (924.4 g, 3.52 moles) in toluene (950 mL) was stirred at reflux for 12 hours. The solid product precipitated from the reaction mixture throughout the course of the reaction. The reaction was allowed to cool to ambient temperature and then cooled to about 5° C. in an ice bath. The solid precipitate was isolated by filtration and dried in vacuo at 25° C. to give a white powder (526.5 g, 92%).

후처리

  1. temperatureat reflux for 12 hours
  2. customThe solid product precipitated from the reaction mixture throughout the course of the reaction
  3. temperaturecooled to about 5° C. in an ice bath
  4. customThe solid precipitate was isolated by filtration
  5. customdried in vacuo at 25° C.

출처 및 근거

ORD 기록
ord-97ed5e42eff14898b0af20e9c961caa6
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07476762B2

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