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Hydrochloric Acid → 7-[3-Aminopiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid dihydrochloride salt

HRID 1455500
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인쇄 미리보기

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HRID 1455500 반응식
[NH2:1][CH:2]1[CH2:7][CH2:6][CH2:5][N:4]([C:8]2[C:17]([O:18][CH3:19])=[C:16]3[C:11]([C:12](=[O:26])[C:13]([C:23]([OH:25])=[O:24])=[CH:14][N:15]3[CH:20]3[CH2:22][CH2:21]3)=[CH:10][CH:9]=2)[CH2:3]1.[ClH:27]>C(O)C>[ClH:27].[ClH:27].[NH2:1][CH:2]1[CH2:7][CH2:6][CH2:5][N:4]([C:8]2[C:17]([O:18][CH3:19])=[C:16]3[C:11]([C:12](=[O:26])[C:13]([C:23]([OH:25])=[O:24])=[CH:14][N:15]3[CH:20]3[CH2:22][CH2:21]3)=[CH:10][CH:9]=2)[CH2:3]1
참가 물질실험 절차출처 및 근거반응 노트

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 9863559Nemonoxacin Impurity 77

생성물 1

HCID 688826357-[3-Aminopiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid dihydrochloride salt

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A quantity of 0.19 g of 7-[3-aminopiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid is suspended in 1.0 mL of ethanol. The pH of the solution is adjusted to 2 with the addition of hydrogen chloride. The desired product is obtained by evaporation of the solvent.

출처 및 근거

ORD 기록
ord-77992d916ad5451fbbf8dbabbf7dbf29
출처 데이터셋
uspto-grants-2009_01
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07482454B2

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