Water → 2-(Benzyloxy)-4-bromobenzaldehyde

HRID 1455981

반응식

HRID 1455981 반응식
[CH2:1](Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]=[O:15])=[C:12]([OH:18])[CH:11]=1.C(=O)([O-])[O-].[K+].[K+].O>CN(C=O)C>[CH2:1]([O:18][C:12]1[CH:11]=[C:10]([Br:9])[CH:17]=[CH:16][C:13]=1[CH:14]=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

6

반응물 4

HCID 962WaterHCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 40660194-Bromo-2-hydroxybenzaldehyde

생성물 1

HCID 156730622-(Benzyloxy)-4-bromobenzaldehyde

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

Benzyl bromide (1.35 ml) was added to a mixture of 4-bromo-2-hydroxybenzaldehyde (2.07 g) and potassium carbonate (1.38 g) in DMF (20 ml) and the mixture was stirred at ambient temperature for 10 hours. The reaction mixture was poured into water (50 ml) to give 2-benzyloxy-4-bromobenzaldehyde as a solid which was filtered and dried, yield 2.88 g. The material was used in subsequent reactions without purification.

출처 및 근거

ORD 기록
ord-5240495585e14aebba79cf7818d27b88
출처 데이터셋
uspto-grants-1998_12
특허 번호
US05843942

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