Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Dimethoxyethane → 1-Bromo-3-(perfluoro-tert-butyl)propane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 반응물 | 2,2-Dibromopropane | HCID 11658 | — |
| 반응물 | Cesium fluoride | HCID 25953 | — |
| 반응물 | 1,1,3,3,3-Pentafluoro-2-(trifluoromethyl)-1-propene | HCID 61109 | — |
| 생성물 | 1-Bromo-3-(perfluoro-tert-butyl)propane | HCID 54255323 | — |
반응 단계
Compound (19) is prepared by a method analogous to the one described by Shinkai et al. (1990, supra). Compound (3) is converted to the sodium salt with excess sodium hydride in a solvent such as tetrahydrofuran or dimethylformamide and then reacted 1-bromo-3-(perfluoro-tert-butyl)propane to furnish Compound (19) which is purified by crystallization or chromatography. 1-bromo-3-(perfluoro-tert-butyl)propane is prepared by reacting perfluoroisobutylene and cesium fluoride in a solvent like monoglyme with excess dibromopropane as described by Rogers et al. (1993, U.S. Pat. No. 5,234,680).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05846515 |
| 출처 데이터셋 | uspto-grants-1998_12 |
| ORD ID | ord-0827a6b3bbc246b9aa23ace1b80091a6 |
| 출처 메모 | uspto-grants-1998_12 |