Veratraldehyde → 2-(3,4-Dimethoxy-alpha-hydroxybenzyl)benzaldehyde dimethylacetal

반응식

[CH3:1][O:2][CH:3]([O:11][CH3:12])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1Br.[CH3:13][O:14][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH:18]=[O:19]>>[CH3:1][O:2][CH:3]([O:11][CH3:12])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:18]([OH:19])[C:17]1[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:15]([O:14][CH3:13])[CH:16]=1

참가 물질

반응물 2

HCID 8419Veratraldehyde

HCID 111489431-Bromo-2-(dimethoxymethyl)benzene

생성물 1

HCID 105435802-(3,4-Dimethoxy-alpha-hydroxybenzyl)benzaldehyde dimethylacetal수율 89%

실험 절차

2-bromobenzaldehyde dimethylacetal and 3,4-dimethoxybenzaldehyde are reacted in the same manner as described in Example 1-(1), whereby 2-(3,4-dimethoxy-α-hydroxybenzyl)benzaldehyde dimethylacetal is obtained as pale yellow syrup.

출처 및 근거

ORD 기록: ord-207c359cdc1043819b46424a88efd4d5
출처 데이터셋: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05070103

반응 노트

불러오는 중…