Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Allyl bromide → 3-Chloro-2-nitrophenyl allyl ether
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Allyl bromide | HCID 7841 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Chloro-2-nitrophenol | HCID 13622170 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 3-Chloro-2-nitrophenyl allyl ether | HCID 19981613 | 84.5% |
반응 단계
4.7g of 3-chloro-2-nitrophenol in 30ml of acetone were treated with 3.7g potassium carbonate and then reacted with 3.25g allylbromide under reflux for 8 hours. The reaction mixture was cooled and filtered and the residue extracted into chloroform, washed once with water, dried using sodium sulphate and 6.5g of an oily residue obtained The crude product was then purified by flash chromatography to give 4.85g of 3-chloro-2-nitrophenyl allyl ether as a colourless oil (yield 84%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05071468 |
| 출처 데이터셋 | uspto-grants-1991_12 |
| ORD ID | ord-c88e7492dff74f3b91785b183962a305 |
| 출처 메모 | uspto-grants-1991_12 |