反应详情

4.7g of 3-chloro-2-nitrophenol in 30ml of acetone were treated with 3.7g potassium carbonate and then reacted with 3.25g allylbromide under reflux for 8 hours. The reaction mixture was cooled and filtered and the residue extracted into chloroform, washed once with water, dried using sodium sulphate and 6.5g of an oily residue obtained The crude product was then purified by flash chromatography to give 4.85g of 3-chloro-2-nitrophenyl allyl ether as a colourless oil (yield 84%).

1. temperatureunder reflux for 8 hours
2. temperatureThe reaction mixture was cooled
3. filtrationfiltered
4. extractionthe residue extracted into chloroform
5. washwashed once with water
6. customdried
7. customobtained The crude product
8. customwas then purified by flash chromatography