Water → 4-chloro-N-hexadecyl-N-methyl-3-nitrobenzenesulfonamide

HRID 1460946노트

반응식

HRID 1460946 반응식
[CH2:1]([NH:17][S:18]([C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([N+:28]([O-:30])=[O:29])[CH:22]=1)(=[O:20])=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[C:31](=O)([O-])[O-].[K+].[K+].COS(OC)(=O)=O.O>CC(C)=O>[CH3:31][N:17]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[S:18]([C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([N+:28]([O-:30])=[O:29])[CH:22]=1)(=[O:19])=[O:20]

참가 물질

6

반응물 4

HCID 962WaterHCID 6497Dimethyl SulfateHCID 11430Potassium CarbonateHCID 14324551HCID 14324551, 화합물

생성물 1

HCID 41628334-chloro-N-hexadecyl-N-methyl-3-nitrobenzenesulfonamide

시약·촉매·용매 1

HCID 180Acetone용매2회

실험 절차

N-Hexadecyl-3-nitro-4-chlorobenzenesulfonamide (170 grams) was dissolved in 640 ml of acetone. 79 grams of potassium carbonate, 6 ml of poly(ethylene glycol) and 71 grams of dimethylsulfate were added and the mixture was heated under reflux for a period of 5 hours. Acetone (240 ml) was added, 870 ml of water was added dropwise at 40° C. and crystals precipitated out on cooling the mixture to room temperature. The crystals were recovered by filtration, washed with water and methanol, and dried.

후처리

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for a period of 5 hours
  3. customcrystals precipitated out
  4. filtrationThe crystals were recovered by filtration
  5. washwashed with water and methanol
  6. customdried

출처 및 근거

ORD 기록
ord-be21a21b5a0543809cc67212913d2f47
출처 데이터셋
uspto-grants-1991_12
특허 번호
US05073473

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