Succinamide → 1-(2-Bromoethyl)pyrrolidine-2,5-dione

HRID 1461416

반응식

HRID 1461416 반응식
[C:1]([NH2:8])(=[O:7])[CH2:2][CH2:3][C:4](N)=[O:5].[Br:9][CH:10](Br)[CH3:11].C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[Br:9][CH2:10][CH2:11][N:8]1[C:1](=[O:7])[CH2:2][CH2:3][C:4]1=[O:5]

참가 물질

5

반응물 3

HCID 8036SuccinamideHCID 112011,1-DibromoethaneHCID 11430Potassium Carbonate

생성물 1

HCID 135613951-(2-Bromoethyl)pyrrolidine-2,5-dione

시약·촉매·용매 1

HCID 6569Methyl Ethyl Ketone용매

실험 절차

49.5 g of succinamide was dissolved in 750 ml of 2-butanone under heating. 187.9 g of dibromoethane and 138 g of anhydrous potassium carbonate were added to the solution and the mixture was heated under reflux for 9.5 h.

후처리

  1. temperatureunder heating
  2. temperaturethe mixture was heated
  3. temperatureunder reflux for 9.5 h.

출처 및 근거

ORD 기록
ord-cea0d1dc653d4b7d987b3ec6529e1f87
출처 데이터셋
uspto-grants-1991_12
특허 번호
US05075335

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