Potassium glycinate → Oleylmethyldihydroxyethylammonium glycinate

HRID 1461636노트

반응식

HRID 1461636 반응식
[Cl-].[CH2:2]([CH2:20][NH2+:21][CH2:22][CH:23]([OH:25])[OH:24])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19].NCC([O-])=O.[K+]>C(O)C(C)C>[NH2:21][CH2:22][C:23]([O-:25])=[O:24].[CH2:2]([CH2:20][NH2+:21][CH2:22][CH:23]([OH:25])[OH:24])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

참가 물질

4

반응물 2

HCID 23673715Potassium glycinateHCID 86745345Oleylmethyldihydroxyethylammonium chloride

생성물 1

HCID 86745343Oleylmethyldihydroxyethylammonium glycinate수율 193.1%

시약·촉매·용매 1

HCID 6560Isobutanol용매

실험 절차

A four-necked flask fitted with stirrer and condenser means was charged with 40.5 g of oleylmethyldihydroxyethylammonium chloride, 13 g of potassium glycinate and 200 g of isobutyl alcohol and the reaction was conducted at 40°-50° C. in an atmosphere of nitrogen gas introduced at a low flow rate for 6 hours. The precipitate was then collected by filtration and washed with 30 ml of isobutyl alcohol. The filtrate and the washings were combined and concentrated under reduced pressure. The residue was dissolved in 200 g of toluene and filtered. The filtrate was then concentrated to give 43.1 g (theoretical yield 44.4 g) of oleylmethyldihydroxyethylammonium glycinate as a waxy product. The elemental analysis and infrared absorption data are given below.

후처리

  1. customA four-necked flask fitted with stirrer and condenser means
  2. customwas conducted at 40°-50° C. in an atmosphere of nitrogen gas
  3. additionintroduced at a low flow rate for 6 hours
  4. filtrationThe precipitate was then collected by filtration
  5. washwashed with 30 ml of isobutyl alcohol
  6. concentrationconcentrated under reduced pressure
  7. dissolutionThe residue was dissolved in 200 g of toluene
  8. filtrationfiltered
  9. concentrationThe filtrate was then concentrated

출처 및 근거

ORD 기록
ord-03d8183a1c0442c08c4699066a63a5f4
출처 데이터셋
uspto-grants-1991_12
특허 번호
US05076828

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