Ethanethiol → HCID 13336875, 화합물

HRID 1462290노트

반응식

HRID 1462290 반응식
[C:1]([C:3]1[C:8]([C:9]#[N:10])=[N:7][C:6](Cl)=[C:5]([CH3:12])[N:4]=1)#[N:2].[CH2:13]([SH:15])[CH3:14].[OH-].[Na+]>>[C:1]([C:3]1[C:8]([C:9]#[N:10])=[N:7][C:6]([S:15][CH2:13][CH3:14])=[C:5]([CH3:12])[N:4]=1)#[N:2]

참가 물질

4

반응물 3

HCID 6343EthanethiolHCID 14798Sodium HydroxideHCID 129071985-Chloro-6-methylpyrazine-2,3-dicarbonitrile

생성물 1

HCID 13336875HCID 13336875, 화합물수율 45%

실험 절차

2,3-Dicyano-5-chloro-6-methylpyrazine (1.79 g; 0.01 mole), 0.62 g (0.01 mole) of ethanethiol and 0.40 g (0.01 mole) of sodium hydroxide were worked up in the same way as in Example 8. Recrystallization from ethanol afforded 0.91 g (yield 45%) of 2,3-dicyano-5-ethylthio-6-methylpyrazine.

후처리

  1. customRecrystallization from ethanol

출처 및 근거

ORD 기록
ord-8e34c42eb7994a84976a28b6aeb1d464
출처 데이터셋
uspto-grants-1984_07
특허 번호
US04460403

반응 노트

불러오는 중…