Hydrochloric Acid → 2-Amino-1-(thiophen-2-yl)ethan-1-one hydrochloride

HRID 1462418노트

반응식

HRID 1462418 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:10]C=[N:8][C:7]=1C(OC)=O.[ClH:15]>>[ClH:15].[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([CH2:7][NH2:8])=[O:10]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 13105420Methyl 5-(thiophen-2-yl)-1,3-oxazole-4-carboxylate

생성물 1

HCID 126098332-Amino-1-(thiophen-2-yl)ethan-1-one hydrochloride수율 93%

실험 절차

53.9 g of 5-(2-thienyl)-4-methoxycarbonyloxazole and 200 ml of 6N hydrochloric acid are treated in the same manner as described in Preparation 1-(2). 42.5 g of N-[(2-thienylcarbonyl)methyl]amine hydrochloride are thereby obtained. Yield: 93%

후처리

  1. customas described in Preparation 1-(2)

출처 및 근거

ORD 기록
ord-e82bf5606a414a3bb259fcda3782b7bd
출처 데이터셋
uspto-grants-1984_07
특허 번호
US04460596

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