Styrene → HCID 20452417, 화합물

반응식

[Cl:1][C:2]1[C:3]([OH:11])=[C:4]([CH:7]=[C:8]([Cl:10])[CH:9]=1)[CH2:5]O.[CH2:12]=[CH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[Cl:10][C:8]1[CH:7]=[C:4]2[C:3](=[C:2]([Cl:1])[CH:9]=1)[O:11][CH:13]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH2:12][CH2:5]2

참가 물질

반응물 2

HCID 7501Styrene

HCID 2411963,5-Dichlorosalicyl alcohol

생성물 1

HCID 20452417HCID 20452417, 화합물

실험 절차

3,5-Dichloro-2-hydroxybenzyl alcohol (4.0 g) and styrene (2.19 g) were heated together at 190° C. for 3 hr. The required 6,8-dichloroflavan was obtained on chromatography of the crude reaction mixture on alumina, eluting with toluene-petroleum ether (b.p. 60°-80° C.) 1:1, and recrystallised from petroleum ether (b.p. 60°-80° C.) to yield 2.60 g, m.p. 74°-76° C.

출처 및 근거

ORD 기록: ord-16dc1cc11e4a4ddb99170ab34e01399e
출처 데이터셋: uspto-grants-1984_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04461907

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