4-Morpholinecarbonitrile → HCID 178423713, 화합물

HRID 1464049노트

반응식

HRID 1464049 반응식
Cl.[NH2:2][C:3]1[CH:8]=[C:7]([CH3:9])[CH:6]=[CH:5][C:4]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[C:16]([N:18]1[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1)#[N:17]>C1C(O)=CC=CC=1C>[CH3:9][C:7]1[CH:6]=[CH:5][C:4]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)=[C:3]([NH:2][C:16]([N:18]2[CH2:23][CH2:22][O:21][CH2:20][CH2:19]2)=[NH:17])[CH:8]=1

참가 물질

4

반응물 2

HCID 737384-MorpholinecarbonitrileHCID 190892224-Methyl[1,1'-biphenyl]-2-amine--hydrogen chloride (1/1)

생성물 1

HCID 178423713HCID 178423713, 화합물

시약·촉매·용매 1

HCID 342M-Cresol용매

실험 절차

A mixture of 2-amino-4-methylbiphenyl hydrochloride (7.7 g) and 4-cyanomorpholine (5.9 g) in m-cresol (45 ml) was heated at 90°-95° C. for 15 hours to yield N-(4-methyl-2-biphenylyl)morpholine-4-carboxamidine (m.p. 154°-155° C.) which was recrystallised from hexane.

후처리

  1. temperaturewas heated at 90°-95° C. for 15 hours

출처 및 근거

ORD 기록
ord-05da2ece5cf0427fb5a2b97bd7992940
출처 데이터셋
uspto-grants-1994_04
특허 번호
US05302720

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