Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chlorophenyl Isocyanate → N-[[(4-chlorophenyl)amino]carbonyl]-3-thiophenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Thiophene-3-sulfonamide | HCID 1201388 | — |
| 용매 | Acetone | HCID 180 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | N-[[(4-chlorophenyl)amino]carbonyl]-3-thiophenesulfonamide | HCID 19089334 | 73.5% |
반응 단계
Procedure of Example 4B was followed with 3-thiophenesulfonamide (1.1 g, 6.81 mmole), acetone (10 ml), 1N NaOH (6.8 ml), 4-chlorophenyl isocyanate (1.05 g, 6.8 mmole) in acetone (10 ml), 1N HCl (8 ml) to give the N-[[(4-chlorophenyl)amino]carbonyl]-3-thiophenesulfonamide (1.44 g, 4 5 mmole).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05302724 |
| 출처 데이터셋 | uspto-grants-1994_04 |
| ORD ID | ord-206a8166634a49178131cce9c5494cf5 |
| 출처 메모 | uspto-grants-1994_04 |