反应详情

Procedure of Example 4B was followed with 3-thiophenesulfonamide (1.1 g, 6.81 mmole), acetone (10 ml), 1N NaOH (6.8 ml), 4-chlorophenyl isocyanate (1.05 g, 6.8 mmole) in acetone (10 ml), 1N HCl (8 ml) to give the N-[[(4-chlorophenyl)amino]carbonyl]-3-thiophenesulfonamide (1.44 g, 4 5 mmole).