Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glycine → Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glycine | HCID 750 | — |
| 반응물 | L-Aspartic Acid | HCID 5960 | — |
| 반응물 | L-Tyrosine | HCID 6057 | — |
| 반응물 | L-Methionine | HCID 6137 | — |
| 반응물 | L-Phenylalanine | HCID 6140 | — |
| 반응물 | Anisole | HCID 7519 | — |
| 반응물 | Thioanisole | HCID 7520 | — |
| 반응물 | 1,2-Ethanedithiol | HCID 10902 | — |
| 반응물 | Sincalide | HCID 9833444 | — |
| 생성물 | Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2 | HCID 444998 | — |
반응 단계
The cleavage yield of CCK-8 peptide, using a similar procedure with scavengers (thioanisole, anisole and 1,2-ethanedithiol) present in the cleavage cocktail, was about 95%. AAA showed a composition of: Asp 2.03, Gly 1.04, Met 1.92, Tyr 0.99, Phe 1.02, which is characteristic of CCK-8.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05306562 |
| 출처 데이터셋 | uspto-grants-1994_04 |
| ORD ID | ord-78eed412d5a6423db2dc1185692fcbc0 |
| 출처 메모 | uspto-grants-1994_04 |