o-Cumenyl chloroformate → Benzene, 1-chloro-2-(1-methylethyl)-

HRID 1464712노트

반응식

HRID 1464712 반응식
[Cl-:1].[Al+3].[Cl-].[Cl-].ClC(O[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH:15]([CH3:17])[CH3:16])=O>>[CH:15]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[Cl:1])([CH3:17])[CH3:16]

참가 물질

3

반응물 2

HCID 6365464o-Cumenyl chloroformateHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 16377Benzene, 1-chloro-2-(1-methylethyl)-수율 20%

반응 조건

온도
200 °C

실험 절차

0.35 g of anhydrous aluminium chloride was added to 25 g of 2-isopropylphenyl chloroformate and the mixture was heated at 200° C. for 3 hours at normal pressure. The reaction mixture was cooled and worked up as described in Example 1. 2-Isopropylchlorobenzene was obtained in a yield of 20%, which is considerable despite the unfavourable substitution pattern.

후처리

  1. temperatureThe reaction mixture was cooled

출처 및 근거

ORD 기록
ord-0c4624d1938140769baec1ebe948d82c
출처 데이터셋
uspto-grants-1994_04
특허 번호
US05306849

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