Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 1-(4-Fluorophenyl)-4-methoxy-pyrazole-3-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 1-(4-fluorophenyl)-4-methoxy-1H-pyrazole-3-carboxylic acid | HCID 33676673 | — |
| 생성물 | 1-(4-Fluorophenyl)-4-methoxy-pyrazole-3-carbonyl chloride | HCID 86708159 | — |
반응 단계
E2 (100 mg, 0.42 mmol, 1.0 eq.) was heated in thionyl chloride (1 mL) for 4 h under reflux. Solvent was removed in vacuo and the crude material was resolved in dry toluene and evaporated under reduced pressure again to yield E3. The crude material was used in the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08999982B2 |
| 출처 데이터셋 | uspto-grants-2015_04 |
| ORD ID | ord-2fa6be84054c46c6b1d9512238ebc798 |
| 출처 메모 | uspto-grants-2015_04 |