Pyrrolidine → (4-Methoxy-8-methylnaphthalen-1-yl)(pyrrolidin-1-yl)methanone

반응식

[CH3:1][O:2][C:3]1[C:12]2[C:7](=[C:8]([CH3:13])[CH:9]=[CH:10][CH:11]=2)[C:6]([C:14]([OH:16])=O)=[CH:5][CH:4]=1.[NH:17]1[CH2:21][CH2:20][CH2:19][CH2:18]1>>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[C:8]([CH3:13])[CH:9]=[CH:10][CH:11]=2)[C:6]([C:14]([N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)=[O:16])=[CH:5][CH:4]=1

참가 물질

반응물 2

HCID 31268Pyrrolidine

HCID 68282059HCID 68282059, 화합물

생성물 1

HCID 68281961(4-Methoxy-8-methylnaphthalen-1-yl)(pyrrolidin-1-yl)methanone

실험 절차

4-Methoxy-8-methyl-1-naphthoic acid (Step-5 of Intermediate-22) was reacted with pyrrolidine by following the similar procedure as described in Step-6 of Intermediate-22.

출처 및 근거

ORD 기록: ord-8d68ec4d5b5c452381250d9fbb9875b0
출처 데이터셋: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09006442B2

반응 노트

불러오는 중…