Sodium hydride → HCID 53241085, 화합물

HRID 1475986노트

반응식

HRID 1475986 반응식
[C:1]([O:4][NH:5][C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7])(=[O:3])[CH3:2].[H-].[Na+].[O:15]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[CH:17]=[C:16]1[S:24](Cl)(=[O:26])=[O:25]>>[C:1]([O:4][N:5]([C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7])[S:24]([C:16]1[O:15][C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[CH:17]=1)(=[O:25])=[O:26])(=[O:3])[CH3:2]

참가 물질

4

반응물 3

HCID 24758Sodium hydrideHCID 27951721-Benzofuran-2-sulfonyl chlorideHCID 10058028(Acetyloxy)-carbamic acid tert-butyl ester

생성물 1

HCID 53241085HCID 53241085, 화합물

실험 절차

N-[(tert-Butoxy)carbonyl]1-benzofuran-2-sulfonamido acetate (105) is prepared from [(tert-butoxy)carbonyl]amino acetate, sodium hydride and 1-benzofuran-2-sulfonyl chloride according to Scheme 2. δH (250 MHz, DMF) 8.07 (1H, d, 0.9 Hz), 7.91 (1H, d, 7.3 Hz), 7.82 (1H, dd, 8.5, 0.8 Hz), 7.64 (1H, td, 7.8, 1.4 Hz), 7.41-7.52 (1H, m), 2.32 (3H, s), 1.37 (9H, s).

출처 및 근거

ORD 기록
ord-6e92901855814e598c2ee74dc94ed084
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09018411B2

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