Hydrochloric Acid → 4-(4-((R)-(4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)-N-(4-((R)-4-(ethyl(2-hydroxyethyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide

반응식

Cl.O1CCOCC1.[Si]([O:15][CH2:16][CH2:17][N:18]([CH2:77][CH3:78])[CH2:19][CH2:20][C@@H:21]([NH:30][C:31]1[CH:36]=[CH:35][C:34]([S:37]([NH:40][C:41](=[O:69])[C:42]2[CH:47]=[CH:46][C:45]([N:48]3[CH2:53][CH2:52][CH:51]([C@H:54]([C:56]4[CH:61]=[CH:60][CH:59]=[CH:58][C:57]=4[C:62]4[CH:67]=[CH:66][C:65]([Cl:68])=[CH:64][CH:63]=4)[OH:55])[CH2:50][CH2:49]3)=[CH:44][CH:43]=2)(=[O:39])=[O:38])=[CH:33][C:32]=1[S:70]([C:73]([F:76])([F:75])[F:74])(=[O:72])=[O:71])[CH2:22][S:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)(C(C)(C)C)(C)C>C(Cl)Cl>[Cl:68][C:65]1[CH:66]=[CH:67][C:62]([C:57]2[CH:58]=[CH:59][CH:60]=[CH:61][C:56]=2[C@H:54]([OH:55])[CH:51]2[CH2:50][CH2:49][N:48]([C:45]3[CH:46]=[CH:47][C:42]([C:41]([NH:40][S:37]([C:34]4[CH:35]=[CH:36][C:31]([NH:30][C@H:21]([CH2:20][CH2:19][N:18]([CH2:77][CH3:78])[CH2:17][CH2:16][OH:15])[CH2:22][S:23][C:24]5[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=5)=[C:32]([S:70]([C:73]([F:74])([F:75])[F:76])(=[O:71])=[O:72])[CH:33]=4)(=[O:38])=[O:39])=[O:69])=[CH:43][CH:44]=3)[CH2:53][CH2:52]2)=[CH:63][CH:64]=1