Dimethylformamide → N,N,N-Trimethyl-N-[3-(tris-trimethylsiloxy-silyl)-propyl]ammonium iodide

HRID 1478941노트

반응식

HRID 1478941 반응식
NC[CH2:3][CH2:4][Si:5]([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])([O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[O:6][Si:7]([CH3:10])([CH3:9])[CH3:8].[CH3:21][I:22].C(=O)([O-])[O-].[Na+].[Na+].[CH3:29][N:30]([CH3:33])[CH:31]=O>>[I-:22].[CH3:29][N+:30]([CH3:33])([CH3:21])[CH2:31][CH2:3][CH2:4][Si:5]([O:11][Si:12]([CH3:13])([CH3:15])[CH3:14])([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])[O:6][Si:7]([CH3:8])([CH3:9])[CH3:10]

참가 물질

5

반응물 4

HCID 6228DimethylformamideHCID 6328Methyl iodideHCID 10340Sodium CarbonateHCID 2756547(3-Aminopropyl)tris(trimethylsiloxy)silane

생성물 1

HCID 86670508N,N,N-Trimethyl-N-[3-(tris-trimethylsiloxy-silyl)-propyl]ammonium iodide

실험 절차

0.8 g of 3-aminopropyltris(trimethylsiloxy)silane, 1.8 g of methyl iodide and 1.35 g of sodium carbonate are added to 50 ml of dimethylformamide. The reaction mixture is stirred for 3 hours at room temperature. The solvent is evaporated and the residue taken in methylene chloride and water. The organic phase is then washed with water, dried and evaporated whereby compound (35) is obtained; 1H-NMR (ppm, CDCl3): 3.45-3.32 11H m, 1.68-1.58 2H m, 0.39 2H t, 0.00 27H s.

후처리

  1. customThe solvent is evaporated
  2. washThe organic phase is then washed with water
  3. customdried
  4. customevaporated whereby compound (35)
  5. customis obtained

출처 및 근거

ORD 기록
ord-c15b8169feb64484b8e0892570a0f430
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09403987B2

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