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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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tert-Butyl carbamate → 2-(Tert-butoxycarbonylamino)-6-chloroisonicotinic acid

HRID 148
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인쇄 미리보기

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HRID 148 반응식
CC(C)(C)OC(N)=O.O=C(O)c1cc(Cl)nc(Cl)c1>C1COCCO1.CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=P([O-])([O-])[O-].[K+].[K+].[K+].[Pd].[Pd]>CC(C)(C)OC(=O)Nc1cc(C(=O)O)cc(Cl)n1
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참가 물질

7

반응물 2

HCID 77922tert-Butyl carbamateHCID 948302,6-Dichloroisonicotinic acid

생성물 1

HCID 722120522-(Tert-butoxycarbonylamino)-6-chloroisonicotinic acid수율 0%

시약·촉매·용매 4

HCID 62657Potassium Phosphate, Tribasic시약HCID 6360441,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)촉매HCID 9811564Bis(dibenzylideneacetone)palladium촉매HCID 312751,4-Dioxane용매

반응 조건

온도
100 °C

실험 절차

Reagents were mixed in a 25 mL round bottom flask and flushed well with nitrogen - heated at 100 °C for 16 h. The mixture looked dark black. Could not detect any starting material or product! It was discarded.

출처 및 근거

ORD 기록
ord-7c9ead47a3324fac997f2b8af6afca02
출처 데이터셋
750 AstraZeneca ELN dataset
원본 링크
출처 보기

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