Hydrochloric Acid → HCID 178483276, 화합물
반응식
[CH3:1][N:2]([CH2:10][CH2:11][CH:12]1[CH2:17][CH2:16][N:15](C(OC(C)(C)C)=O)[CH2:14][CH2:13]1)[C:3]([C:5]1[N:6]=[N:7][NH:8][CH:9]=1)=[O:4].Cl.O1CCOCC1>CCOC(C)=O>[CH3:1][N:2]([CH2:10][CH2:11][CH:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1)[C:3]([C:5]1[N:6]=[N:7][NH:8][CH:9]=1)=[O:4]참가 물질
5
실험 절차
To tert-butyl 4-(2-(N-methyl-1H-1,2,3-triazole-4-carboxamido)ethyl)piperidine-1-carboxylate (step 2) (190 mg, 0.563 mmol) in EtOAc (5 ml) was added 4N HCl in dioxane (5 ml, 20.00 mmol). The mixture was stirred for 30 mins and concentrated under reduced pressure to give crude N-methyl-N-(2-(piperidin-4-yl)ethyl)-1H-1,2,3-triazole-4-carboxamide as a gum. This was used in the next step without further purification.
후처리
- concentrationconcentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-8058b4b6dee845188f043dfeccfb93b0
- 출처 데이터셋
- uspto-grants-2016_08
- 특허 번호
- US09409895B2
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