Diisopropylethylamine → {(3S,5S)-1-{(S)-2-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-propionylamino]-2-cyclohexyl-acetyl}-5-[(R)-(1,2,3,4-tetrahydro-naphthalen-1-yl)carbamoyl]-pyrrolidin-3-yl}-carbamic acid 9H-fluoren-9-ylmethyl ester

반응식

[N:1]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])([CH3:7])[C@H:2]([C:4]([OH:6])=O)[CH3:3].CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.[CH:48]1[C:60]2[CH:59]([CH2:61][O:62][C:63](=[O:93])[NH:64][C@H:65]3[CH2:69][C@@H:68]([C:70](=[O:82])[NH:71][C@H:72]4[C:81]5[C:76](=[CH:77][CH:78]=[CH:79][CH:80]=5)[CH2:75][CH2:74][CH2:73]4)[N:67]([C:83](=[O:92])[C@@H:84]([NH2:91])[CH:85]4[CH2:90][CH2:89][CH2:88][CH2:87][CH2:86]4)[CH2:66]3)[C:58]3[C:53](=[CH:54][CH:55]=[CH:56][CH:57]=3)[C:52]=2[CH:51]=[CH:50][CH:49]=1>CN(C=O)C.C(OCC)(=O)C>[CH:48]1[C:60]2[CH:59]([CH2:61][O:62][C:63](=[O:93])[NH:64][C@H:65]3[CH2:69][C@@H:68]([C:70](=[O:82])[NH:71][C@H:72]4[C:81]5[C:76](=[CH:77][CH:78]=[CH:79][CH:80]=5)[CH2:75][CH2:74][CH2:73]4)[N:67]([C:83](=[O:92])[C@@H:84]([NH:91][C:4](=[O:6])[C@@H:2]([N:1]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[CH3:7])[CH3:3])[CH:85]4[CH2:90][CH2:89][CH2:88][CH2:87][CH2:86]4)[CH2:66]3)[C:58]3[C:53](=[CH:54][CH:55]=[CH:56][CH:57]=3)[C:52]=2[CH:51]=[CH:50][CH:49]=1