Azetidine → 6-(Azetidin-1-yl)pyridine-3,4-diamine

반응식

[N:1]1([C:7]2[CH:12]=[C:11]([NH2:13])[C:10]([N+:14]([O-])=O)=[CH:9][N:8]=2)[CH2:6][CH2:5]OC[CH2:2]1.N1CCC1>>[N:1]1([C:7]2[N:8]=[CH:9][C:10]([NH2:14])=[C:11]([NH2:13])[CH:12]=2)[CH2:6][CH2:5][CH2:2]1

참가 물질

반응물 2

HCID 10422Azetidine

HCID 900216182-(Morpholin-4-yl)-5-nitropyridin-4-amine

생성물 1

HCID 900217496-(Azetidin-1-yl)pyridine-3,4-diamine

실험 절차

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 151.1 and 151.2, except azetidine was used in place of morpholine.

출처 및 근거

ORD 기록: ord-847fb57143484f2f97bab58b4da218d9
출처 데이터셋: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09428502B2

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