Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1491135생성일: 2026년 10월 26일
Benzene, 1-methyl-4-(methylthio)- → 4,4,5,5-Tetramethyl-2-(5-methyl-2-(methylthio)phenyl)-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491135
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzene, 1-methyl-4-(methylthio)- | HCID 69334 | — |
| 시약 | 4,4'-Dimethyl-2,2'-bipyridine | HCID 14338 | — |
| 시약 | Bis(pinacolato)diborane | HCID 2733548 | — |
| 촉매 | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| 용매 | P-Xylene | HCID 7809 | — |
| 생성물 | 4,4,5,5-Tetramethyl-2-(5-methyl-2-(methylthio)phenyl)-1,3,2-dioxaborolane | HCID 138983642 | 41% |
| 생성물 | HCID 178503150 | HCID 178503150 | 20% |
반응 단계
dtbpy: A mixture of ortho- and meta-borylated products (79 mg, 61% yield, ortho/meta + para = 2.0); meta-Isomer 5d was obtained by further purification by GPC (18 mg, 14% yield), yellow solid (mp. 85-87 oC)
출처 및 근거
| DOI | 10.1002/anie.201610041 |
|---|
| 출처 데이터셋 | Borylation dataset from Roche |
|---|
| ORD ID | ord-8ab19278bad6421ab2de79245143ed07 |
|---|
| 출처 메모 | Borylation dataset from Roche |
|---|
