Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1491140생성일: 2026년 10월 26일
4-Phenylthioanisole → 4,4,5,5-Tetramethyl-2-(2-methylsulfanyl-5-phenylphenyl)-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491140
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Phenylthioanisole | HCID 11019897 | — |
| 시약 | Bis(pinacolato)diborane | HCID 2733548 | — |
| 시약 | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| 촉매 | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| 용매 | P-Xylene | HCID 7809 | — |
| 생성물 | 4,4,5,5-Tetramethyl-2-(2-methylsulfanyl-5-phenylphenyl)-1,3,2-dioxaborolane | HCID 132510262 | 86% |
반응 단계
Ligand 3f: A mixture of ortho- and meta-borylated products (140 mg, 86% yield, ortho/meta + para = >30); ortho-borylated product 4g was obtained by further purification by GPC (128 mg, 79% yield), white solid (mp. 116-118 oC)
출처 및 근거
| DOI | 10.1002/anie.201610041 |
|---|
| 출처 데이터셋 | Borylation dataset from Roche |
|---|
| ORD ID | ord-a2d89378380b4f06b6a03649928343ec |
|---|
| 출처 메모 | Borylation dataset from Roche |
|---|
