N-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamide → N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

HRID 1491183

반응식

HRID 1491183 반응식
O=C(Nc1c(F)c(F)c(C(F)(F)F)c(F)c1F)c1ccccc1>CC#N.CC(=O)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=P(O)(O)O.O=S(=O)(O)OOS(=O)(=O)O.[K].[K].[Pd]>CC1(C)OB(c2ccccc2C(=O)Nc2c(F)c(F)c(C(F)(F)F)c(F)c2F)OC1(C)C

참가 물질

7

반응물 1

HCID 86708425N-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamide

생성물 1

HCID 101557522N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide수율 0%

시약·촉매·용매 5

HCID 2733548Bis(pinacolato)diborane시약HCID 16218557Phosphoric acid (potassium)시약HCID 43835029CID 43835029시약HCID 587591933375-31-3촉매HCID 6342Acetonitrile용매

반응 조건

온도
80 °C

출처 및 근거

ORD 기록
ord-5b98816e1190428b94fa33e753a756ac
출처 데이터셋
Borylation dataset from Roche

연결된 노트

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