Epinephrine → Dopamine

HRID 1492750

반응식

HRID 1492750 반응식
C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[CH:14]1[C:19]([C@@H:20](O)[CH2:21][NH2:22])=[CH:18][C:17]([OH:24])=[C:16]([OH:25])[CH:15]=1.CNC[C@H](O)C1C=CC(O)=C(O)C=1>C(#N)C>[NH2:22][CH2:21][CH2:20][C:19]1[CH:14]=[CH:15][C:16]([OH:25])=[C:17]([OH:24])[CH:18]=1

참가 물질

5

반응물 3

HCID 5816EpinephrineHCID 31348CitrateHCID 439260Norepinephrine

생성물 1

HCID 681Dopamine수율 96.9%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

The results shown in FIGS. 6 and 7 were obtained using a solvent of 95% 0.05 m citrate buffer with a pH of 5.2 and 5% acetonitrile with a flow rate of 0.8 ml/min. In FIGS. 6 and 7, peak 1 represents the solvent front, peak 2 represents 4.9 ng norepinephrine and peak 3 represents 4.88 ng epinephrine. Peak 4 was produced by dopamine (4.30 ng).

후처리

  1. custom6 and 7 were obtained

출처 및 근거

ORD 기록
ord-a4d2c75e019745efb68ff20089f38f71
출처 데이터셋
uspto-grants-1994_12
특허 번호
US05374892

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