2-Chlorotoluene → 2,2'-Dimethylbiphenyl

HRID 1493109

반응식

HRID 1493109 반응식
[C:1]([Mg]Cl)([CH3:4])([CH3:3])[CH3:2].Cl[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH3:14].[CH2:15]1[CH2:19]OC[CH2:16]1>>[CH3:2][C:1]1[CH:4]=[CH:19][CH:15]=[CH:16][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH3:14]

참가 물질

4

반응물 3

HCID 72382-ChlorotolueneHCID 8028TetrahydrofuranHCID 178418310HCID 178418310, 화합물

생성물 1

HCID 117972,2'-Dimethylbiphenyl

실험 절차

All of the following runs were made with 1 mmol NiBr2 and 24 mmol t-butylmagnesium chloride in THF at reflux for 16 hours. Protic ligands were converted to their magnesium salts by the addition of an equivalent amount of a Grignard reagent prior to addition of 2-chlorotoluene.

후처리

  1. temperatureat reflux for 16 hours

출처 및 근거

ORD 기록
ord-03e5f6c8a9ce4868b0f6ed5a06d7f26a
출처 데이터셋
uspto-grants-1991_06
특허 번호
US05021380

연결된 노트

불러오는 중…