Ammonium Hydroxide → 5-(4-Chlorophenyl)furan-2-carboxamide

반응식

[NH4+:1].[OH-].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:14][C:13]([C:15](Cl)=[O:16])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1>>[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:14][C:13]([C:15]([NH2:1])=[O:16])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1

참가 물질

반응물 2

HCID 14923Ammonium Hydroxide

HCID 27719705-(4-chlorophenyl)furan-2-carbonyl Chloride

생성물 1

HCID 47800015-(4-Chlorophenyl)furan-2-carboxamide

실험 절차

To 1000 ml. of cold, stirring NH4OH, 63 g. (0.26 mole) of 5-(p-chlorophenyl)-2-furoyl chloride is added portionwise. The resulting mixture is stirred at ice bath temperature for 15 minutes and then is stored at room temperature for 18 hours. The solid is filtered, is washed with water and is dried at 60° to yield 56 g. (97%).

후처리

waitis stored at room temperature for 18 hours
filtrationThe solid is filtered
washis washed with water
customis dried at 60°
customto yield 56 g

출처 및 근거

ORD 기록: ord-2245ed9770494de7b665cb3ba76866c2
출처 데이터셋: uspto-grants-1991_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05023272

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