Potassium ethylxanthate → HCID 178505573, 화합물

HRID 1493875노트

반응식

HRID 1493875 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[NH2:9].CCO[C:13]([S-])=[S:14].[K+]>C(O)C.O>[F:8][C:4]1[C:3]2[N:9]=[C:13]([SH:14])[NH:1][C:2]=2[CH:7]=[CH:6][CH:5]=1

참가 물질

5

반응물 2

HCID 2735045Potassium ethylxanthateHCID 27828353-Fluorobenzene-1,2-diamine

생성물 1

HCID 178505573HCID 178505573, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

1,2-diamino-3-fluorobenzene (1.6 g, 12.7 mmol) and potassium ethyl xanthogenate (2.64 g, 16.5 mmol) were dissolved in ethanol (25 ml) and water (6 ml). The mixture was refluxed for 14 hours and then concentrated on a rotavapor. Water (20 ml) was added and the solution was acidified with 2M hydrochloric acid. The precipitate was filtered off and dried. In this way the title compound was obtained (1.23 g, 58%). NMR is given below.

후처리

  1. temperatureThe mixture was refluxed for 14 hours
  2. concentrationconcentrated on a rotavapor
  3. additionWater (20 ml) was added
  4. filtrationThe precipitate was filtered off
  5. customdried

출처 및 근거

ORD 기록
ord-bf69e5297fa04ddda244cc93dbc5dd34
출처 데이터셋
uspto-grants-1991_06
특허 번호
US05025024

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