Hydrochloric Acid → HCID 54206520, 화합물

HRID 1494296노트

반응식

HRID 1494296 반응식
[NH2:1][C:2]1[CH:17]=[CH:16][C:5]([CH2:6][CH2:7][C:8]2[CH:14]=[C:13]([OH:15])[CH:12]=[CH:11][C:9]=2[OH:10])=[CH:4][CH:3]=1.CC(N(C)C)=O.[CH2:24]([S:32](Cl)(=[O:34])=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31].Cl>N1C=CC=CC=1>[CH2:24]([S:32]([NH:1][C:2]1[CH:17]=[CH:16][C:5]([CH2:6][CH2:7][C:8]2[CH:14]=[C:13]([OH:15])[CH:12]=[CH:11][C:9]=2[OH:10])=[CH:4][CH:3]=1)(=[O:34])=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 31374DimethylacetamideHCID 822611-Octanesulfonyl chlorideHCID 125250502-[2-(4-Aminophenyl)ethyl]-1,4-benzenediol

생성물 1

HCID 54206520HCID 54206520, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

In 1 l-volume three-necked flask were charged 100 g of (4-aminophenethyl)hydroquinone, 500 ml of dimethylacetamide, and 36 ml of pyridine, and 85 ml of octanesulfonyl chloride were slowly added dropwise thereto at room temperature while stirring. After the dropwise addition, the stirring was continued for 4 hours. The reaction mixture was poured into a hydrochloric acid aqueous solution and extracted with ethyl acetate. The extract was washed with water, dried over magnesium sulfate, and concentrated to obtain 129 g of the entitled compound as an oily substance.

후처리

  1. additionwere slowly added dropwise
  2. additionAfter the dropwise addition
  3. extractionextracted with ethyl acetate
  4. washThe extract was washed with water
  5. dry with materialdried over magnesium sulfate
  6. concentrationconcentrated

출처 및 근거

ORD 기록
ord-2558cc6cc1274ea9bd819c6873c27e45
출처 데이터셋
uspto-grants-1991_06
특허 번호
US05026634

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