참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Thiophenol | HCID 7969 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 1-Propanone, 2-chloro-2-methyl-1-phenyl- | HCID 81985 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1-Propanone, 2-methyl-1-phenyl-2-(phenylthio)- | HCID 12270589 | — |
반응 단계
10.88 g of a 50% suspension of sodium hydride in paraffin mineral oil are fed into 100 ml of DMF, followed slowly by 25.11 g of thiophenol. When dissolution is complete (65° C.), the solution is cooled to 2° C. and 36.5 g of 2-chloro-2-methylpropiophenone are fed in over 30 minutes maintaining the temperature below 10° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05026740 |
|---|
| 출처 데이터셋 | uspto-grants-1991_06 |
|---|
| ORD ID | ord-5752ad7ba6814d479c4aac8bf2293d7c |
|---|
| 출처 메모 | uspto-grants-1991_06 |
|---|
