Sodium Hydroxide → HCID 71556225, 화합물
반응식
C([O:3][C:4]([C:6]1[C:7]([CH:24]([CH3:26])[CH3:25])=[N:8][C:9]2[C:14]([C:15]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[F:22])=[CH:13][CH:12]=[C:11]([Cl:23])[CH:10]=2)=[O:5])C.[OH-].[Na+]>C(O)C>[Cl:23][C:11]1[CH:10]=[C:9]2[C:14]([C:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[F:22])=[C:6]([C:4]([OH:5])=[O:3])[C:7]([CH:24]([CH3:25])[CH3:26])=[N:8]2)=[CH:13][CH:12]=1참가 물질
4
실험 절차
The title compound was prepared in analogy to example 6 step B from a mixture of 7-chloro-4-(2-fluoro-phenyl)-2-isopropyl-quinoline-3-carboxylic acid ethyl ester and 1N NaOH in ethanol. White solid. MS (ESI): 344.1 (M+H)+.
출처 및 근거
- ORD 기록
- ord-618e1a0d218b4e06960487f0fd7fd6c5
- 출처 데이터셋
- uspto-grants-2015_12
- 특허 번호
- US09199938B2
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