Sodium Hydroxide → HCID 71556228, 화합물

HRID 1497052노트

반응식

HRID 1497052 반응식
C([O:3][C:4]([C:6]1[C:7]([CH:25]2[CH2:27][CH2:26]2)=[N:8][C:9]2[C:14]([C:15]=1[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[Cl:23])=[CH:13][C:12]([Cl:24])=[CH:11][CH:10]=2)=[O:5])C.[OH-].[Na+]>C(O)C>[Cl:24][C:12]1[CH:13]=[C:14]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH:25]1[CH2:27][CH2:26]1)[C:6]([C:4]([OH:5])=[O:3])=[C:15]2[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[Cl:23]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 86682929HCID 86682929, 화합물

생성물 1

HCID 71556228HCID 71556228, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The title compound was prepared in analogy to example 6 step B from a mixture of 6-chloro-4-(2-chloro-benzyl)-2-cyclopropyl-quinoline-3-carboxylic acid ethyl ester and 1N NaOH in ethanol. White solid. MS (ESI): 372.0 (M+H)+.

출처 및 근거

ORD 기록
ord-768cf51c9d474c1580920d430aef719a
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09199938B2

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